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Construction of sustainable, colored and multifunctional protein silk fabric using biomass riboflavin

《化学科学与工程前沿（英文）》 2023年 第17卷 第8期   页码 1131-1139 doi: 10.1007/s11705-023-2321-0

摘要： Riboflavin sodium phosphate has been confirmed as a promising biomass product derived from natural plants. In this paper, a novel method of dyeing and multifunctional modification of silk fabric by impregnation with riboflavin sodium phosphate was proposed, such that protein silk fabric can be endowed with bright yellow color and multi-functionality. The results of this paper confirmed that the pH and concentration of riboflavin sodium phosphate solution are critical factors for dyeing and multifunctional modification. Attractively, the photochromic performance was one of the most distinctive features of the modified silk fabric, and the dyed silk fabric turned into fluorescent green from original yellow under 365 nm ultraviolet lamp. Furthermore, the modified silk fabric exhibited good antibacterial properties with a high inhibition rate of 92% for Escherichia coli. Besides, the flame retardancy of silk fabric was significantly improved after modification. The damaged length of modified silk fabric with 40% owf riboflavin sodium phosphate was lower than 10.4 cm and passed the B1 classification. As revealed by the result of this paper, riboflavin sodium phosphate is sufficiently effective in serving as an eco-friendly multifunctional agent for strengthening the add-value of silk textiles.

关键词： biomass     riboflavin sodium phosphate     silk protein     multifunctional modification     flame retardant    

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A novel strategy for the construction of silk fibroin–SiO composite aerogel with enhanced mechanical

《化学科学与工程前沿（英文）》 2023年 第17卷 第3期   页码 288-297 doi: 10.1007/s11705-022-2222-7

摘要： The practical application of silica aerogels is an enormous challenge due to the difficulties in improving both mechanical property and thermal insulation performance. In this work, silk fibroin was used as scaffold to improve the mechanical property and thermal insulation performance of silica aerogels. The ungelled SiO2 precursor solution was impregnated into silk fibroin to prepare silk fibroin–SiO2 composite aerogels via sol−gel method followed by freeze-drying. By virtue of the interfacial hydrogen-bonding interactions and chemical reactions between silk fibroin and silica nanoparticles, SiO2 was well-dispersed in the silk fibroin aerogel and composite aerogels exhibited enhanced mechanical property. By increasing the loading of silk fibroin from 15 wt % to 21 wt %, the maximum compressive stress was enhanced from 0.266 to 0.508 MPa when the strain reached 50%. The thermal insulation performance of the composite aerogels was improved compared with pure silica aerogel, as evidenced that the thermal conductivity was decreased from 0.0668 to 0.0341 W∙m‒1∙K‒1. Moreover, the composite aerogels exhibited better hydrophobicity and fire retardancy compared to pure silica aerogel. Our work provides a novel approach to preparing silk fibroin–SiO2 composite aerogels with enhanced mechanical property and thermal insulation performance, which has potential application as thermal insulation material.

关键词： silica aerogel     silk fibroin     impregnation     thermal insulation     mechanical property    

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Structural synthesis of ancient Chinese foot-operated silk-reeling mechanism

Kuohung HSIAO, Yuhsun CHEN, Hongsen YAN,

《机械工程前沿（英文）》 2010年 第5卷 第3期   页码 279-288 doi: 10.1007/s11465-010-0101-2

摘要： This work synthesizes the structures of the foot-operated silk-reeling mechanism, which was vaguely depicted in many literatures in ancient China. Based on the analysis of the mechanism, the structural characteristics and design constraints of the mechanism with indeterminate links and joints are concluded. Then, according to the concepts of generalization and specialization subject to the concluded design constraints, all feasible structures of the mechanism that met the technological standards of the subject’s time period are reconstructed. This reconstruction process provides a logical foundation to better understanding, clarification, and suggestions for the issue of ancient mechanical drawings with indeterminate links and joints.

关键词： silk-reeling mechanism     structure of mechanism     reconstruction design     history of machinery    

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Determination of energy dissipation of a spider silk structure under impulsive loading

Jorge ALENCASTRE,Carlos MAGO,Richard RIVERA

《机械工程前沿（英文）》 2015年 第10卷 第3期   页码 306-310 doi: 10.1007/s11465-015-0349-7

摘要：

Various researches and studies have demonstrated that spider silk is much stronger and more deformable than a steel string of the same diameter from a mechanical approach. These excellent properties have caused many scientific disciplines to get involved, such as bio-mechanics, bio-materials and bio-mimetics, in order to create a material of similar properties and characteristics. It should be noted that the researches and studies have been oriented mainly as a quasi-static model. For this research, the analysis has taken a dynamic approach and determined the dissipation energy of a structure which is made of spider silk “Dragline” and produced by the Argiope-Argentata spider, through an analytical-experimental way, when being subjected to impulsive loading. Both experimental and analytical results, the latter obtained by using adjusted models, have given high levels of dissipation energy during the first cycle of vibration, which are consistent with the values suggested by other authors.

关键词： dissipation energy     impact     visco-elastic material     spider silk    

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Durable and recyclable BiOBr/silk fibroin-cellulose acetate composite film for efficient photodegradation

《化学科学与工程前沿（英文）》 2023年 第17卷 第11期   页码 1765-1775 doi: 10.1007/s11705-023-2323-y

摘要： A stable and recyclable of BiOBr/silk fibroin-cellulose acetate composite film was prepared by blending-wet phase transformation and in situ precipitate technology. The cellulose acetate film modified by silk fibroin formed a finger-shaped porous structure, which provided a large space for the uniform growth of BiOBr nanosheets and facilitated the shuttle flow of dyes in film. The morphology, phase structure, and optical properties of the composite films were characterized using various techniques, and their photocatalytic performance for dye wastewater was evaluated under visible light irradiation. Results showed that the BiOBr/SF-CA composite film exhibited efficient photocatalytic activity with 99.9% of rhodamine B degradation rate. Moreover, the composite film maintained high catalytic stability because Bi as the active species deposited on the film showed almost no loss. Finally, the possible photocatalytic mechanisms in the BiOBr/SF-CA composite film were speculated through radical-trapping experiments and electron spin resonance testing.

关键词： BiOBr nanosheet     cellulose acetate     silk fibroin     photocatalytic degradation     dye wastewater    

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Silk Roads for the 21st Century: Engineering Mega-Infrastructure for Development and Sustainability

Tony Marjoram

《工程管理前沿（英文）》 2016年 第3卷 第3期   页码 187-196 doi: 10.15302/J-FEM-2016038

摘要： Infrastructure facilitates the movement of people, the production and distribution of goods and services, and underpins development. Infrastructure is expensive and long-lasting, and needs long-term policy, planning and management, in terms of design, construction, operation and maintenance. Infrastructure relates particularly to engineering and technology. All technological change brings economic, social, cultural and environmental change, planned and unpredicted. Mega levels of technology bring mega levels of change, effects and impacts. Mega infrastructure such as the Silk Road Economic Belt and 21st Century Maritime Silk Road, the “One Belt, One Road” (OBOR) initiative, announced by President Xi Jinping in 2013, will require equally mega policy, planning and management. This paper will discuss policy, planning and management issues relating to mega infrastructure and the OBOR initiative, with particular reference to energy, communications, transportation, health, emergency preparedness and response, and less predictable areas of change, for example in disease prevention and control, within the overall need for economic, environmental and ecological sustainability. The paper will discuss associated needs for education, training and capacity building in engineering. The paper will also refer to lessons learnt from the original Silk Road in the context of the development of civilizations and intercultural dialogue through the transfer of goods, services, technologies, ideas, knowledge, customs, cultures and philosophies, less predictable and unwanted transfers, for example of disease, and the need for awareness, policy, planning and management of such wider issues.

关键词： infrastructure     growth     development     sustainability     change     new Silk Roads    

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冰上丝绸之路海洋科技创新战略研究

李大海,张荧楠

《中国工程科学》 2019年 第21卷 第6期   页码 64-70 doi: 10.15302/J-SSCAE-2019.06.012

摘要：

“冰上丝绸之路”共建是我国参与北极保护、开发与治理的重要途径。科技创新是我国推进“冰上丝绸之路”共建的重要支撑。我国在北极科学考察、科研基础设施建设、装备研发制造等方面已经具有一定的基础，但也存在统筹机制弱、投入不足、平台建设滞后等问题。应围绕《中国的北极政策》白皮和“冰上丝绸之路”共建的有关原则，大力推进北极海洋认知、保护、开发和治理相关科学技术创新和人文社科研究，在北极海洋观测、海洋海冰研究、生物和生态系统研究、污染防治、气候变化响应、航运技术、油气开发技术等方面谋求取得更大突破。通过加强双边多边合作、发起国际大科学计划、建立公共平台、加强人才交流与培养等方式，推动“冰上丝绸之路”科技创新不断走向深入。

关键词： “冰上丝绸之路”     海洋科技     “一带一路”    

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加强“21世纪海上丝绸之路”战略支点建设研究

张大勇

《中国工程科学》 2016年 第18卷 第2期   页码 105-110 doi: 10.15302/J-SSCAE-2016.02.013

摘要：

21世纪海上丝绸之路战略支点是指承载我国与沿线国家经贸、科技、文化合作功能的空间区域。近年来，我国与沿线国家在经贸合作园区、交通基础设施建设等方面开展了广泛合作，取得了良好效果，但也存在顶层设计不清晰、空间布局不合理、合作方式较单一、合作层次不丰富等问题。本研究以围绕“五通”加强战略支点建设为研究目标，在我国对外贸易数据分析为基础，利用层次分析法和德尔菲法，提出了战略支点建设的重点区域和建设模式，并从推进经贸合作区建设、加强科技文化交流、深化地区与行业合作等方面提出了政策建议。

关键词： 21世纪海上丝绸之路     战略支点     经贸合作     科技合作    

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Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction

Hong LI,Ziding ZHANG

《农业科学与工程前沿（英文）》 2016年 第3卷 第2期   页码 102-112 doi: 10.15302/J-FASE-2016100

摘要： Plants are frequently affected by pathogen infections. To effectively defend against such infections, two major modes of innate immunity have evolved in plants; pathogen-associated molecular pattern-triggered immunity and effector-triggered immunity. Although the molecular components as well as the corresponding pathways involved in these two processes have been identified, many aspects of the molecular mechanisms of the plant immune system remain elusive. Recently, the rapid development of omics techniques (e.g., genomics, proteomics and transcriptomics) has provided a great opportunity to explore plant–pathogen interactions from a systems perspective and studies on protein–protein interactions (PPIs) between plants and pathogens have been carried out and characterized at the network level. In this review, we introduce experimental and computational identification methods of PPIs, popular PPI network analysis approaches, and existing bioinformatics resources/tools related to PPIs. Then, we focus on reviewing the progress in genome-wide PPI networks related to plant–pathogen interactions, including pathogen-centric PPI networks, plant-centric PPI networks and interspecies PPI networks between plants and pathogens. We anticipate genome-wide PPI network analysis will provide a clearer understanding of plant–pathogen interactions and will offer some new opportunities for crop protection and improvement.

关键词： plant–pathogen interactions     systems biology     omics     plant immunity     protein–protein interaction     network    

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“21世纪海上丝绸之路”蓝色经济国际合作：驱动因素、领域识别与机制构建

陈明宝,韩立民

《中国工程科学》 2016年 第18卷 第2期   页码 98-104 doi: 10.15302/J-SSCAE-2016.02.012

摘要：

当今世界，蓝色经济已经成为全球海洋领域发展的重点，它强调的是海洋经济的可持续发展，突出国家间通过通力合作共同促进海洋资源开发与海洋生态环境保护。“21世纪海上丝绸之路”建设恰为中国与沿线国家的蓝色经济合作提供重要平台。从这一关系为切入点，研究沿线国家蓝色经济合作的驱动因素，构建包括国家战略发展、区域比较优势、政府政策导向、区域环境安全在内的蓝色经济合作领域选择依据，在考虑蓝色经济合作的一般领域的基础上，选择了资源能源、海洋产业、海洋科技、海洋生态环境作为中国与沿线国家合作的重点领域，并针对合作领域构建了以市场主导、陆海统筹、协作治理与利益协调为框架的合作机制。

关键词： 21世纪海上丝绸之路     蓝色经济     驱动因素     领域识别     合作机制    

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古丝绸之路铁路畅通关键问题及对策

何华武

《工程（英文）》 2016年 第2卷 第3期   页码 288-291 doi: 10.1016/J.ENG.2016.03.017

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The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases

null

《医学前沿（英文）》 2011年 第5卷 第1期   页码 70-76 doi: 10.1007/s11684-011-0119-9

摘要：

Protein kinase C epsilon (PKC ?) is one of major isoforms in novel PKC family. Although it has been extensively characterized in the past decade, the role of PKC ? in neuron is still not well understood. Advances in molecular biology have now removed significant barriers to the direct investigation of PKC ? functions in vivo, and PKC ? has been increasingly implicated in the neural biological functions and associated neurogenic diseases. Recent studies have provided important insights into the influence of PKC ? on cortical processing at both the single cell level and network level. These studies provide compelling evidence that PKC ? could regulate distinct aspects of neural signal transduction and suggest that the coordinated actions of a number of molecular signals contribute to the specification and differentiation of PKC ? signal pathway in the developing brain.

关键词： protein kinase C ?     signal transduction     neurogenic disease    

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Wheat gluten protein and its impacts on wheat processing quality

Wujun MA, Zitong YU, Maoyun SHE, Yun ZHAO, Shahidul ISLAM

《农业科学与工程前沿（英文）》 2019年 第6卷 第3期   页码 279-287 doi: 10.15302/J-FASE-2019267

摘要：

Before the advent of the wheat genomic era, a wide range of studies were conducted to understand the chemistry and functions of the wheat storage proteins, which are the major determinants of wheat flour the suitability of wheat flour for various end products, such as bread, noodles and cakes. Wheat grain protein is divided into gluten and non-gluten fractions and the wheat processing quality mainly depends on the gluten fractions. Gluten provides the unique extensibility and elasticity of dough that are essential for various wheat end products. Disulfide bonds are formed between cysteine residues, which is the chemical bases for the physical properties of dough. Based on the SDS-extractability, grain protein is divided into SDS-unextractable polymeric protein (UPP) and SDS-extractable polymeric protein. The percentage of UPP is positively related to the formation of disulfide bonds in the dough matrix. In the wheat genomic era, new glutenins with long repetitive central domains that contain a high number of consensus hexapeptide and nonapeptide motifs as well as high content of cysteine and glutamine residues should be targeted.

关键词： wheat gluten     consensus motifs     disulfide bonds     SDS-unextractable polymeric protein     glutenins     gliadins     processing quality     storage protein    

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Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:

null

《医学前沿（英文）》 2018年 第12卷 第3期   页码 319-323 doi: 10.1007/s11684-017-0553-4

摘要：

Antithrombin and protein C are two crucial members in the anticoagulant system and play important roles in hemostasis. Mutations in and lead to deficiency or dysfunction of the two proteins, which could result in venous thromboembolism (VTE). Here, we report a Chinese 22-year-old young man who developed recurrent and serious VTE in cerebral veins, visceral veins, and deep veins of the lower extremity. Laboratory tests and direct sequencing of and were conducted for the patient and his family members. Coagulation tests revealed that the patient presented type I antithrombin deficiency combined with decreased protein C activity resulting from a small insertion mutation c.848_849insGATGT in and a short deletion variant c.572_574delAGA in . This combination of the two mutations was absent in 400 healthy subjects each from southern and northern China. Then, we summarized all the mutations of the and gene reported in the Chinese Han population. This study demonstrates that the combination of antithrombin deficiency and decreased protein C activity can result in severe VTE and that the coexistence of different genetic factors may increase the risk of VTE.

关键词： antithrombin deficiency     protein C activity     mutation     variant     venous thromboembolism     anticoagulants    

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Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology and protein

Baicheng HUANG, Kegong TIAN

《农业科学与工程前沿（英文）》 2020年 第7卷 第2期   页码 218-226 doi: 10.15302/J-FASE-2020324

摘要：

Emergent coronaviruses (CoVs) such as SARS-CoV and MERS-CoV have posed great threats to public health worldwide over the past two decades. Currently, the emergence of SARS-CoV-2 as a pandemic causes greater public health concern. CoV diversity is due to the large size and replication mechanisms of the genomes together with having bats as their optimum natural hosts. The ecological behavior and unique immune characteristics of bats are optimal for the homologous recombination of CoVs. The relationship of spatial structural characteristics of the spike protein, a protein that is critical for recognition by host receptors, in different CoVs may provide evidence in explaining the coevolution of CoVs and their hosts. This information may help to enhance our understanding of CoV evolution and thus provide part of the basis of preparations for any future outbreaks.

关键词： bat     coronavirus     evolution     host receptor     spike protein     transmission    

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标题 作者 时间 类型 操作

Construction of sustainable, colored and multifunctional protein silk fabric using biomass riboflavin

期刊论文

A novel strategy for the construction of silk fibroin–SiO composite aerogel with enhanced mechanical

期刊论文

Structural synthesis of ancient Chinese foot-operated silk-reeling mechanism

Kuohung HSIAO, Yuhsun CHEN, Hongsen YAN,

期刊论文

Determination of energy dissipation of a spider silk structure under impulsive loading

Jorge ALENCASTRE,Carlos MAGO,Richard RIVERA

期刊论文

Durable and recyclable BiOBr/silk fibroin-cellulose acetate composite film for efficient photodegradation

期刊论文

Silk Roads for the 21st Century: Engineering Mega-Infrastructure for Development and Sustainability

Tony Marjoram

期刊论文

冰上丝绸之路海洋科技创新战略研究

李大海,张荧楠

期刊论文

加强“21世纪海上丝绸之路”战略支点建设研究

张大勇

期刊论文

Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction

Hong LI,Ziding ZHANG

期刊论文

“21世纪海上丝绸之路”蓝色经济国际合作：驱动因素、领域识别与机制构建

陈明宝,韩立民

期刊论文

古丝绸之路铁路畅通关键问题及对策

何华武

期刊论文

The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases

null

期刊论文

Wheat gluten protein and its impacts on wheat processing quality

Wujun MA, Zitong YU, Maoyun SHE, Yun ZHAO, Shahidul ISLAM

期刊论文

Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:

null

期刊论文

Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology and protein

Baicheng HUANG, Kegong TIAN

期刊论文